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Atezolizumab neutralizing assay development: a novel way of evaluating assay cutpoint after sample pretreatment

Abstract Atezolizumab, a biotherapeutic monoclonal antibody directed against PD-L1, has been shown to be efficacious in multiple oncology indications. In clinical trials, a subset of patients developed anti-atezolizumab antibodies, necessitating the development of a neutralizing antibody (NAb) assay...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rachel Melendez, Jane Ruppel, Cecilia Leddy, Jenny Yang, Ann Brady, Yenny Webb-Vargas, Jochen Brumm, Lynn Kamen, Yuan Song
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SpringerOpen 2025-02-01
Cyfres:AAPS Open
Mynediad Ar-lein:https://doi.org/10.1186/s41120-024-00105-z
Tagiau: Ychwanegu Tag
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