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Neuroendocrine pathways and breast cancer progression: a pooled analysis of somatic mutations and gene expression from two large breast cancer cohorts

Abstract Background Experimental studies indicate that neuroendocrine pathways might play a role in progression of breast cancer. We aim to test the hypothesis that somatic mutations in the genes of neuroendocrine pathways influence breast cancer prognosis, through dysregulated gene expression in tu...

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Principais autores: Kejia Hu, Chengshi Wang, Chuanxu Luo, Hong Zheng, Huan Song, Jacob Bergstedt, Katja Fall, Ting Luo, Kamila Czene, Unnur A. Valdimarsdóttir, Fang Fang, Donghao Lu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-06-01
Serier:BMC Cancer
Fag:
Breast cancer
Somatic mutation
Differential expression
Pathway
Online adgang:https://doi.org/10.1186/s12885-022-09779-8
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