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ENPP1, an Old Enzyme with New Functions, and Small Molecule Inhibitors—A STING in the Tale of ENPP1

Ectonucleotide pyrophosphatase/phosphodiesterase I (ENPP1) was identified several decades ago as a type II transmembrane glycoprotein with nucleotide pyrophosphatase and phosphodiesterase enzymatic activities, critical for purinergic signaling. Recently, ENPP1 has emerged as a critical phosphodieste...

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Autori principali: Kenneth I. Onyedibe, Modi Wang, Herman O. Sintim
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2019-11-01
Serie:Molecules
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Accesso online:https://www.mdpi.com/1420-3049/24/22/4192
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