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Licochalcone B Induces ROS-Dependent Apoptosis in Oxaliplatin-Resistant Colorectal Cancer Cells via p38/JNK MAPK Signaling

Licochalcone B (LCB) exhibits anticancer activity in oral cancer, lung cancer, and hepatocellular carcinoma cells. However, little is known about its antitumor mechanisms in human oxaliplatin-sensitive and -resistant colorectal cancer (CRC) cells. The purpose of the present study was to investigate...

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Principais autores: Ah-Won Kwak, Woo-Keun Kim, Seung-On Lee, Goo Yoon, Seung-Sik Cho, Ki-Taek Kim, Mee-Hyun Lee, Yung Hyun Choi, Jin-Young Lee, Jin Woo Park, Jung-Hyun Shim
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2023-03-01
Series:Antioxidants
Assuntos:
apoptosis
colorectal cancer
JNK/p38 MAPK
Licochalcone B
reactive oxygen species
Acceso en liña:https://www.mdpi.com/2076-3921/12/3/656
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