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The MEK Inhibitor Trametinib Improves Outcomes following Subarachnoid Haemorrhage in Female Rats

Aneurysmal subarachnoid haemorrhage (SAH) is a haemorrhagic stroke that causes approximately 5% of all stroke incidents. We have been working on a treatment strategy that targets changes in cerebrovascular contractile receptors, by blocking the MEK/ERK1/2 signalling pathway. Recently, a positive eff...

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Bibliografische gegevens
Hoofdauteurs: Jesper Peter Bömers, Anne-Sofie Grell, Lars Edvinsson, Sara Ellinor Johansson, Kristian Agmund Haanes
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2022-11-01
Reeks:Pharmaceuticals
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Online toegang:https://www.mdpi.com/1424-8247/15/12/1446
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