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Irinotecan Hydrochloride Administration Considering Dosing-Time Attenuates Delayed Diarrhea in Rats

<b>Background:</b> Irinotecan hydrochloride (CPT-11) is an important anticancer drug used in a wide range of regimens to treat colorectal and gastric cancers, and one of its severe side effects is delayed diarrhea. Therefore, based on known circadian variations in intestinal function and drug metabo...

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書誌詳細
主要な著者: Hideto To, Mari Tomonari, Makoto Myojin, Fumiyasu Okazaki
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2026-05-01
シリーズ:Pharmaceutics
主題:
オンライン・アクセス:https://www.mdpi.com/1999-4923/18/6/645
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