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Immunoinformatics-driven multi-epitope vaccine design targeting PSMA, STEAP1, and B7H3 for prostate cancer

IntroductionProstate cancer remains a major global health challenge, necessitating precision immunotherapeutic strategies tailored to tumor-associated antigens. This study aimed to design a multi-epitope peptide vaccine targeting prostate-specific membrane antigen (PSMA), six-transmembrane epithelia...

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Hlavní autoři: Stefanus Vicky Bernhard Elisa Runtunuwu, Trina Ekawati Tallei, Hyo Jeong Kim, Moon Nyeo Park, Ismail Celik, Burak Kirilmaz, Grace Lendawati Amelia Turalaki, Fatimawali Fatimawali, Lydia Estelina Naomi Tendean, Martha Marie Kaseke, Dionisius Rafael Makawaehe, Elne Vieke Rambi, Bonglee Kim
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2026-03-01
Edice:Frontiers in Medicine
Témata:
computational vaccine design
immunoinformatics
immunotherapy
multi-epitope
precision medicine
prostate cancer
On-line přístup:https://www.frontiersin.org/articles/10.3389/fmed.2026.1716345/full
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