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Antibody–Drug Conjugates (ADCs): A Review of Structural Design, Technological Evolution, and Future Perspectives

Antibody–drug conjugates (ADCs) have become an important class of targeted anticancer therapeutics by integrating the tumor selectivity of monoclonal antibodies with the potent cytotoxicity of small-molecule payloads through rational linker design. This review summarizes the structural fundamentals...

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Principais autores: Guiying Wu, Zhenhai Yuan, Ming Chen, Xuan Tang, Fang Wang, Daizhou Zhang
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2026-04-01
סדרה:Molecules
נושאים:
antibody–drug conjugates
monoclonal antibody
linker
cytotoxic payload
גישה מקוונת:https://www.mdpi.com/1420-3049/31/7/1180
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