Optineurin provides a mitophagy contact site for TBK1 activation
Abstract Tank-binding kinase 1 (TBK1) is a Ser/Thr kinase that is involved in many intracellular processes, such as innate immunity, cell cycle, and apoptosis. TBK1 is also important for phosphorylating the autophagy adaptors that mediate the selective autophagic removal of damaged mitochondria. How...
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| Principais autores: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Nature
2024-01-01
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| coleção: | The EMBO Journal |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1038/s44318-024-00036-1 |
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