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GATA6 defines endoderm fate by controlling chromatin accessibility during differentiation of human-induced pluripotent stem cells

Summary: In addition to driving specific gene expression profiles, transcriptional regulators are becoming increasingly recognized for their capacity to modulate chromatin structure. GATA6 is essential for the formation of definitive endoderm; however, the molecular basis defining the importance of...

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Autores principales: James A. Heslop, Behshad Pournasr, Jui-Tung Liu, Stephen A. Duncan
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2021-05-01
Colección:Cell Reports
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Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2211124721004848
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