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Resistomycin Induced Apoptosis and Cycle Arrest in Human Hepatocellular Carcinoma Cells by Activating p38 MAPK Pathway In Vitro and In Vivo

Resistomycin, a quinone-related natural antibiotic, has shown strong inhibitory activity against human hepatocellular carcinoma (HCC) in vitro. Here, we investigated the role of p38 MAPK in the pro-apoptotic and G2/M phase arrest action of HCC HepG2 cells upon treatment with resistomycin in vitro an...

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Hoofdauteurs: Zhuo Han, Xingming Zhao, E Zhang, Jiahui Ma, Hao Zhang, Jianjiang Li, Weidong Xie, Xia Li
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2021-09-01
Reeks:Pharmaceuticals
Onderwerpen:
resistomycin
apoptosis
cell cycle arrest
hepatocellular carcinoma
p38 MAPK
Online toegang:https://www.mdpi.com/1424-8247/14/10/958
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