Overcoming β-Cell Dysfunction in Type 2 Diabetes Mellitus: CD36 Inhibition and Antioxidant System

Type 2 diabetes mellitus (T2DM) is marked by chronic hyperglycemia, gradually worsening β-cell failure, and insulin resistance. Glucotoxicity and oxidative stress cause β-cell failure by increasing reactive oxygen species (ROS) production, impairing insulin secretion, and disrupting transcription fa...

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Detalhes bibliográficos

Principais autores:	Il Rae Park, Yong Geun Chung, Kyu Chang Won
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Korean Diabetes Association 2025-01-01
coleção:	Diabetes & Metabolism Journal
Assuntos:	cd36 antigens diabetes mellitus, type 2 hyperglycemia insulin-secreting cells oxidative stress reactive oxygen species
Acesso em linha:	http://e-dmj.org/upload/pdf/dmj-2024-0796.pdf
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