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In Silico Evaluation of a Promising Key Intermediate Thieno [2,3-d] Pyrimidine Derivative with Expected JAK2 Kinase Inhibitory Activity

This work describes the synthesis and the cytotoxic evaluation of thiophene and thienopyrimidine derivatives. The investigated compound was subjected to target prediction that indicated its high affinity to kinases and to Janus kinase 2 (JAK2) specifically. Molecular docking screening was performed...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Elshaymaa I. Elmongy, Hanan Ali Henidi
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2022-03-01
Rangatū:Molbank
Ngā marau:
Urunga tuihono:https://www.mdpi.com/1422-8599/2022/1/M1352
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