SIRT5–RNF126 coordinated regulation of METTL17 stability controls mitochondrial function and glioma progression
Abstract Gliomas are highly invasive brain tumors in which metabolic reprogramming plays a pivotal role in tumor initiation and progression. METTL17, a mitochondria-associated methyltransferase, has been reported to enhance oxidative phosphorylation (OXPHOS) through mitochondrial RNA methylation; ho...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BMC
2026-04-01
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| シリーズ: | Cell & Bioscience |
| 主題: | |
| オンライン･アクセス: | https://doi.org/10.1186/s13578-026-01570-7 |
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