Hypoxia-inducible factor-1α promotes tubulointerstitial fibrosis via the upregulation of Muc4

Tubulointerstitial fibrosis (TIF) is the common final outcome of almost all progressive chronic kidney diseases (CKDs). Hypoxia-inducible factor-1 (HIF-1) activation plays an essential role in CKD; however, the specific contribution of tubular HIF-1 to renal TIF remains unclear. In the current study...

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Detalhes bibliográficos

Principais autores:	Zhong-Tang Li, Xin-Hui Hu, Wei-Jie Ni, Zuo-Lin Li, Bi-Kun Huang, Yu Zhang, A-Feng Miao, Jing-Yuan Cao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2025-12-01
coleção:	Renal Failure
Assuntos:	Tubulointerstitial fibrosis HIF-1α Muc4 chronic kidney disease
Acesso em linha:	https://www.tandfonline.com/doi/10.1080/0886022X.2025.2501757
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