Generation of three human induced pluripotent stem cell lines with IRX5 knockout and knockin genetic editions using CRISPR-Cas9 system

Studies on animal models have shown that Irx5 is an important regulator of cardiac development and that it regulates ventricular electrical repolarization gradient in the adult heart. Mutations in IRX5 have also been linked in humans to cardiac conduction defects. In order to fully characterize the...

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Bibliografische gegevens

Hoofdauteurs:	Robin Canac, Amandine Caillaud, Bastien Cimarosti, Aurore Girardeau, Hanan Hamamy, Bruno Reversade, Carine Bonnard, Zeina R. Al Sayed, Laurent David, Jeremie Poschmann, Patricia Lemarchand, Guillaume Lamirault, Nathalie Gaborit
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2022-01-01
Reeks:	Stem Cell Research
Online toegang:	http://www.sciencedirect.com/science/article/pii/S1873506121004748
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