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Deletion of a Single LeishIF4E-3 Allele by the CRISPR-Cas9 System Alters Cell Morphology and Infectivity of <italic toggle="yes">Leishmania</italic>

ABSTRACT The genomes of Leishmania and trypanosomes encode six paralogs of the eIF4E cap-binding protein, known in other eukaryotes to anchor the translation initiation complex. In line with the heteroxenous nature of these parasites, the different LeishIF4E paralogs vary in their biophysical featur...

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Detaylı Bibliyografya
Asıl Yazarlar: Rohit Shrivastava, Nitin Tupperwar, Matan Drory-Retwitzer, Michal Shapira
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2019-10-01
Seri Bilgileri:mSphere
Konular:
Online Erişim:https://journals.asm.org/doi/10.1128/mSphere.00450-19
Etiketler: Etiketle
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