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Protective effects of Dioscin against sepsis‐induced cardiomyopathy via regulation of toll‐like receptor 4/MyD88/p65 signal pathway

Abstract Background Dioscin has many pharmacological effects; however, its role in sepsis‐induced cardiomyopathy (SIC) is unknown. Accordingly, we concentrate on elucidating the mechanism of Dioscin in SIC rat model. Methods The SIC rat and H9c2 cell models were established by lipopolysaccharide (LP...

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Principais autores: Meng Zhang, Deyuan Zhi, Pei Liu, Yajun Wang, Meili Duan
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2024-05-01
Serier:Immunity, Inflammation and Disease
Fag:
Dioscin
lipopolysaccharide
MyD88
sepsis‐induced cardiomyopathy
TLR4
Online adgang:https://doi.org/10.1002/iid3.1229
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