Evaluation of the structural models of the human reference proteome: AlphaFold2 versus ESMFold

The human reference proteome is routinely modelled with predictive tools such as AlphaFold2. We recently released a database in which, for each human protein, the AlphaFold2 model is paired with its ESMFold counterpart. The two predictive methods take advantage of different procedures and it is inte...

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Bibliografiska uppgifter

Huvudupphov:	Matteo Manfredi, Castrense Savojardo, Pier Luigi Martelli, Rita Casadio
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Elsevier 2025-06-01
Serie:	Current Research in Structural Biology
Ämnen:	Human protein structure prediction AI computed structural models Structural model quality assessment Model secondary structure Model solvent accessibility AlphaFold2
Länkar:	http://www.sciencedirect.com/science/article/pii/S2665928X25000042
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