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Increased α‐tocopherol metabolism in horses with equine neuroaxonal dystrophy

Abstract Background Equine neuroaxonal dystrophy/equine degenerative myeloencephalopathy (eNAD/EDM) is an inherited neurodegenerative disorder associated with a vitamin E deficiency within the first year of life. Vitamin E consists of 8 isoforms metabolized by the CYP4F2 enzyme. No antemortem diagno...

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Автори: Erin N. Hales, Hadi Habib, Gianna Favro, Scott Katzman, R. Russell Sakai, Sabin Marquardt, Matthew H. Bordbari, Brittni Ming‐Whitfield, Janel Peterson, Anna R. Dahlgren, Victor Rivas, Carolina Alanis Ramirez, Sichong Peng, Callum G. Donnelly, Bobbi‐Sue Dizmang, Angelica Kallenberg, Robert Grahn, Andrew D. Miller, Kevin Woolard, Benjamin Moeller, Birgit Puschner, Carrie J. Finno
Формат: Artigo
Мова:Inglês
Опубліковано: Oxford University Press 2021-09-01
Серія:Journal of Veterinary Internal Medicine
Предмети:
ataxia
cytochrome P450
equine degenerative myeloencephalopathy
genetics
vitamin E
Онлайн доступ:https://doi.org/10.1111/jvim.16233
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