Establishment of cell culture model and humanized mouse model of chronic hepatitis B virus infection

ABSTRACT The absence of a hepatitis B virus (HBV) infection system has constrained the study of the viral life cycle and the development of antiviral drugs. We previously established a hepatocellular carcinoma cell line, HLCZ01, that can support the entire life cycle of HBV. To further optimize the...

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Detalles Bibliográficos

Principais autores:	Renyun Tian, Di Yang, Biaoming Xu, Rilin Deng, Binbin Xue, Luoling Wang, Huiyi Li, Qian Liu, Xiaohong Wang, Songqing Tang, Mengyu Wan, Hua Pei, Haizhen Zhu
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology 2024-01-01
Series:	Microbiology Spectrum
Assuntos:	HBV persistence cell culture model animal model kinetics of antigen virion secretion
Acceso en liña:	https://journals.asm.org/doi/10.1128/spectrum.02745-23
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