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Detecting epistasis with the marginal epistasis test in genetic mapping studies of quantitative traits.

Epistasis, commonly defined as the interaction between multiple genes, is an important genetic component underlying phenotypic variation. Many statistical methods have been developed to model and identify epistatic interactions between genetic variants. However, because of the large combinatorial se...

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Hlavní autoři: Lorin Crawford, Ping Zeng, Sayan Mukherjee, Xiang Zhou
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2017-07-01
Edice:PLoS Genetics
On-line přístup:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1006869&type=printable
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