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β-actin dependent chromatin remodeling mediates compartment level changes in 3D genome architecture

β-actin loss can affect gene expression and heterochromatin organization. Here the authors conduct a comprehensive genomic analysis of β-actin knockout mouse embryonic fibroblasts (MEFs) to investigate the impact of changes in β-actin levels on 3d genome architecture and chromatin remodeling activit...

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Bibliografiske detaljer
Principais autores: Syed Raza Mahmood, Xin Xie, Nadine Hosny El Said, Tomas Venit, Kristin C. Gunsalus, Piergiorgio Percipalle
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2021-09-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/s41467-021-25596-2
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