Application of machine learning to predict unbound drug bioavailability in the brain
Purpose: Optimizing brain bioavailability is highly relevant for the development of drugs targeting the central nervous system. Several pharmacokinetic parameters have been used for measuring drug bioavailability in the brain. The most biorelevant among them is possibly the unbound brain-to-plasma p...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2024-04-01
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| Serie: | Frontiers in Drug Discovery |
| Soggetti: | |
| Accesso online: | https://www.frontiersin.org/articles/10.3389/fddsv.2024.1360732/full |
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