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Using Neutrons to Elucidate the Catalytic Shift from Superoxide Dismutase to Peroxidase Activity in Fe-Substituted Human MnSOD

Human manganese superoxide dismutase (MnSOD2) is a metallo-oxidoreductase localized to the mitochondrial matrix. Its canonical function is as an antioxidant, neutralizing superoxide radicals generated during the electron transport chain (ETC). By converting superoxide into hydrogen peroxide and mole...

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Hlavní autoři: Miles Graham, Gloria E. O. Borgstahl
Médium: Artigo
Jazyk:Inglês
Vydáno: AIP Publishing LLC and ACA 2025-10-01
Edice:Structural Dynamics
On-line přístup:https://pubs.aip.org/aca/sdy/article-pdf/12/5_Supplement/A114/20775437/a114_1_4.0000905.pdf
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