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Robust anti-tubercular profile of Solanum virginianum extract in enhancing isoniazid bioavailability and curtailing stress tolerance in Mycobacterium smegmatis

IntroductionThe formidable survival mechanisms employed by Mycobacterium tuberculosis (Mtb), combined with the low bioavailability of anti-tubercular drugs and their associated hepatotoxicity, worsen tuberculosis management. Traditional medicinal plants offer potential solutions to these challenges....

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Main Authors: Acharya Balkrishna, Monali Joshi, Manisha Kabdwal, Meenu Tomer, Savita Lochab, Anurag Varshney
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Microbiology
Subjects:
mc2155
isoniazid
adjunct therapy
tuberculosis
stress tolerance
targeted metabolomics
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1429027/full
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