Сandidate SNP-markers of rheumatoid arthritis that can significantly alter the affinity of the TATA-binding protein for human gene promoters

Rheumatoid polyarthritis (RA) is an autoimmune disease with autoantibodies, including antibodies to citrullant antigens and proinflammatory cytokines, such as TNF-α and IL-6, which are involved in the induction of chronic synovitis, bone erosion, followed by deformity. Immunopathogenesis is based on...

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Principais autores:	I. V. Chadaeva, D. A. Rasskazov, E. B. Sharypova, I. A. Drachkova, E. A. Oshchepkova, L. K. Savinkova, P. M. Ponomarenko, M. P. Ponomarenko, N. A. Kolchanov, V. A. Kozlov
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2020-01-01
Colecção:	Вавиловский журнал генетики и селекции
Assuntos:	tata binding protein (tbp) tbp-binding site (tata box) promoter tbp-promoter affinity gene single nucleotide polymorphism (snp) gene expression significant change snp-marker rheumatoid polyarthritis (ra)
Acesso em linha:	https://vavilov.elpub.ru/jour/article/view/2398
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