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Negativeome characterization and decontamination in early-life virome studies

Abstract Contaminant sequences of external origin complicate the study of host-associated viromes, particularly in low-biomass samples obtained through viral-like particle (VLP) enrichment. However, the prevalence and impact of external contaminants on low-biomass samples are under-studied. Here, we...

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Main Authors: Nataliia Kuzub, Alexander Kurilshikov, Alexandra Zhernakova, Sanzhima Garmaeva
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2025-07-01
Serija:Nature Communications
Online dostop:https://doi.org/10.1038/s41467-025-61478-7
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