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Microfluidic Formulation of DNA-Loaded Multicomponent Lipid Nanoparticles for Gene Delivery

In recent years, lipid nanoparticles (LNPs) have gained considerable attention in numerous research fields ranging from gene therapy to cancer immunotherapy and DNA vaccination. While some RNA-encapsulating LNP formulations passed clinical trials, DNA-loaded LNPs have been only marginally explored s...

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Autori principali: Erica Quagliarini, Serena Renzi, Luca Digiacomo, Francesca Giulimondi, Barbara Sartori, Heinz Amenitsch, Valentina Tassinari, Laura Masuelli, Roberto Bei, Lishan Cui, Junbiao Wang, Augusto Amici, Cristina Marchini, Daniela Pozzi, Giulio Caracciolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2021-08-01
Serie:Pharmaceutics
Soggetti:
lipid nanoparticles
microfluidics
transfection efficiency
lipofectamine
Accesso online:https://www.mdpi.com/1999-4923/13/8/1292
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