Interactions of human autoantibodies with hippocampal GABAergic synaptic transmission – analyzing antibody-induced effects ex-vivo

Autoantibodies (aAB) to the presynaptic located enzyme glutamate decarboxylase 65 (GAD65) are a characteristic attribute for a variety of autoimmune diseases of the central nervous system including subtypes of limbic encephalitis, stiff person-syndrome, cerebellar ataxia, and Batten´s disease. Clini...

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Bibliografski detalji

Glavni autori:	Holger eHaselmann, Luise eRöpke, Christian eWerner, Albrecht eKunze, Christian eGeis
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2015-06-01
Serija:	Frontiers in Neurology
Teme:	Hippocampus Limbic Encephalitis Autoantibody GABAergic inhibition patch-clamp recording GAD65
Online pristup:	http://journal.frontiersin.org/Journal/10.3389/fneur.2015.00136/full
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