The variation landscape of CYP2D6 in a multi-ethnic Asian population
Abstract Cytochrome P450 2D6 (CYP2D6) plays a crucial role in metabolizing approximately 20% of medications prescribed clinically. This enzyme is encoded by the CYP2D6 gene, known for its extensive polymorphism with over 170 catalogued haplotypes or star alleles, which can have a profound impact on...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2024-07-01
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| Serier: | Scientific Reports |
| Online adgang: | https://doi.org/10.1038/s41598-024-67691-6 |
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