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Establishment and application of unbiased in vitro drug screening assays for the identification of compounds against Echinococcus granulosus sensu stricto.

Echinococcus multilocularis and E. granulosus s.l. are the causative agents of alveolar and cystic echinococcosis, respectively. Drug treatment options for these severe and neglected diseases are limited to benzimidazoles, which are not always efficacious, and adverse side effects are reported. Thus...

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Autores principales: Marc Kaethner, Matías Preza, Tobias Kaempfer, Pascal Zumstein, Claudia Tamponi, Antonio Varcasia, Andrew Hemphill, Klaus Brehm, Britta Lundström-Stadelmann
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2023-08-01
Colección:PLoS Neglected Tropical Diseases
Acceso en línea:https://doi.org/10.1371/journal.pntd.0011343
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