Strategically isolated bacteriophages targeting ETEC K88 (F4) alleviate post-weaning diarrhea in piglets via modulation of gut microbiota and inflammatory responses

Abstract Background Post-weaning diarrhea (PWD) in piglets, primarily caused by enterotoxigenic Escherichia coli (ETEC) K88 (F4) infection, presents a major challenge in swine production. This study aimed to isolate bacteriophages (phages) specific to ETEC K88, utilizing ETEC K88 as the host strain,...

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Detalhes bibliográficos

Principais autores:	Yan Chen, Minfeng Ding, Xingping Chen, Tiande Zou, Yi Liu, Jun Chen, Jinming You
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-01-01
Colecção:	Journal of Animal Science and Biotechnology
Assuntos:	Bacteriophages ETEC K88 Gut microbiota Inflammation Post-weaning diarrhea Weaned piglets
Acesso em linha:	https://doi.org/10.1186/s40104-025-01322-6
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