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Synthesis, spectral analysis and biological evaluation of 2-{[(morpholin-4-yl)ethyl]thio}-5-phenyl/aryl-1,3,4-oxadiazole derivatives

A series of new derivatives of 4-(2-chloroethyl)morpholine hydrochloride (5) were efficiently synthesized. Briefly, different aromatic organic acids (1a-f) were refluxed to acquire respective esters (2a-f) using conc. H2SO4 as catalyst. The esters were subjected to nucleophillic substitution by mono...

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Hoofdauteurs: Aziz-ur-Rehman, Samreen Gul Khan, Syed Ali Raza Naqvi, Matloob Ahmad, Naheed Akhtar, Tanveer Hussain Bokhari, Muhammad Irfan, Ali Usman, Sidra Batool, Shahid Rasool, Syed Adnan Ali Shah, Muhammad Shahid
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: University of Karachi 2021-01-01
Reeks:Pakistan Journal of Pharmaceutical Sciences
Online toegang:https://pjps.pk/single-article?id=cmrtz0ad502wz8xgux5q0x1t5
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