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The role and mechanism of p53 F229V mutation in inhibiting pseudorabies virus replication

The p53 protein is a key transcription factor that regulates cellular responses to stress and is widely recognized as a host restriction factor against various viral infections. However, its specific role in pseudorabies virus (PRV) replication, pathogenesis, and host response remains unclear. This...

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Bibliographic Details
Main Authors: Cuilian Yu, Jingshuai Zhang, Shumin Chen, Zhao Wang, Liqi Zhu, Kezhou Wang
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2025-11-01
Series:Frontiers in Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1628916/full
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