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Mutant p53 and TP53 mutations in esophageal squamous cell carcinoma: consistency and diagnostic significance

Background and objectiveTP53 mutation is an initiating event in tumorigenesis in many cancers. Mutant p53 expression is an important manifestation of TP53 mutations, however, this association has not yet been confirmed in esophageal squamous cell carcinoma (ESCC). This study comprised three componen...

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Principais autores: Xueyu Zhuang, Na Lin, Yanjuan Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-02-01
coleção:Frontiers in Genetics
Assuntos:
consistency analysis
diagnostic value
esophageal squamous cell carcinoma
p53
TP53
whole exome sequencing
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fgene.2026.1680422/full
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