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Complex RNA Secondary Structures Mediate Mutually Exclusive Splicing of Coleoptera Dscam1

Mutually exclusive splicing is an important mechanism for expanding protein diversity. An extreme example is the Down syndrome cell adhesion molecular (Dscam1) gene of insects, containing four clusters of variable exons (exons 4, 6, 9, and 17), which potentially generates tens of thousands of protei...

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Hlavní autoři: Haiyang Dong, Lei Li, Xiaohua Zhu, Jilong Shi, Ying Fu, Shixin Zhang, Yang Shi, Bingbing Xu, Jian Zhang, Feng Shi, Yongfeng Jin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021-03-01
Edice:Frontiers in Genetics
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fgene.2021.644238/full
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