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(+)-Borneol inhibits neuroinflammation and M1 phenotype polarization of microglia in epileptogenesis through the TLR4-NFκB signaling pathway

ObjectiveTo investigate the effect of (+)-borneol on neuroinflammation and microglia phenotype polarization in epileptogenesis and its possible mechanism.MethodsBased on mouse models of status epilepticus (SE) induced by pilocarpine, and treated with 15 mg/kg (+)-borneol, western-blot was used to de...

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Auteurs principaux: Shuo Li, Alhamdu Adamu, Yucai Ye, Fankai Gao, Rulin Mi, Guofang Xue, Zhaojun Wang
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2024-11-01
Collection:Frontiers in Neuroscience
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fnins.2024.1497102/full
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