The Microtus fortis chromosome-level genome: illuminating adaptive evolution and natural parasite immunity

Abstract The reed vole (Microtus fortis) serves as a significant rodent model, particularly distinguished by its robust natural resistance to Schistosoma japonicum infection. To unravel the genetic basis of this remarkable immunity, we present the first chromosome-level genome assembly for M. fortis...

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Detalhes bibliográficos

Principais autores:	Du Zhang, Qianwen Zhou, Qi Hu, Tianqiong He, Jieling Xiao, Junkang Zhou, Yixin Wen, Qian Liu, Jing Zhang, Wenlin Zhi, Lingxuan Ouyang, Suisui Gao, Ruotong Guan, Zhijun Zhou
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-02-01
coleção:	BMC Genomics
Assuntos:	Microtus fortis Genome assembly Schistosoma japonicum resistance Adaptive evolution MHC gene expansion Comparative genomics
Acesso em linha:	https://doi.org/10.1186/s12864-026-12573-6
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