Protein disulfide isomerase modulation of TRPV1 controls heat hyperalgesia in chronic pain

Summary: Protein disulfide isomerase (PDI) plays a key role in maintaining cellular homeostasis by mediating protein folding via catalyzing disulfide bond formation, breakage, and rearrangement in the endoplasmic reticulum. Increasing evidence suggests that PDI can be a potential treatment target fo...

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Principais autores:	Yongxue Zhang, Qi Miao, Sai Shi, Han Hao, Xinmeng Li, Zeyao Pu, Yakun Yang, Hailong An, Wei Zhang, Youzhen Kong, Xu Pang, Cunyang Gu, Nikita Gamper, Yi Wu, Hailin Zhang, Xiaona Du
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2022-04-01
Series:	Cell Reports
Assuntos:	CP: Neuroscience
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2211124722003734
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