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YiaC and CobB regulate lysine lactylation in Escherichia coli

The characterization of lysine lactylation (Kla) in prokaryotes remains unclear. Here, the authors identify the regulatory enzymes (YiaC as a lactylase and CobB as a delactylase) and functional network of Kla and reveal a Kla-mediated molecular mechanism for glycolysis regulation in Escherichia coli...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Hanyang Dong, Jianji Zhang, Hui Zhang, Yue Han, Congcong Lu, Chen Chen, Xiaoxia Tan, Siyu Wang, Xue Bai, Guijin Zhai, Shanshan Tian, Tao Zhang, Zhongyi Cheng, Enmin Li, Liyan Xu, Kai Zhang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2022-11-01
Schriftenreihe:Nature Communications
Online-Zugang:https://doi.org/10.1038/s41467-022-34399-y
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