ISGylation is induced in neurons by demyelination driving ISG15-dependent microglial activation
Abstract The causes of grey matter pathology and diffuse neuron injury in MS remain incompletely understood. Axonal stress signals arising from white matter lesions has been suggested to play a role in initiating this diffuse grey matter pathology. Therefore, to identify the most upstream transcript...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2022-10-01
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| Colecção: | Journal of Neuroinflammation |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s12974-022-02618-4 |
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