Alpha7 Nicotinic Acetylcholine Receptor Mediates Nicotine-induced Apoptosis and Cell Cycle Arrest of Hepatocellular Carcinoma HepG2 Cells

Purpose: The cytotoxic properties upon treatment with nicotine have been reported in several studies, but the underlying mechanisms remain not fully defined. The alpha7 nicotinic acetylcholine receptor (α7nAChR) is one of the important nicotinic receptors, which nicotine partly by binding to this re...

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Detalhes bibliográficos

Principais autores:	Khalil Hajiasgharzadeh, Mohammad Hossein Somi, Behzad Mansoori, Mohammad Amin Doustvandi, Fatemeh Vahidian, Mohsen Alizadeh, Ahad Mokhtarzadeh, Dariush Shanehbandi, Behzad Baradaran
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Tabriz University of Medical Sciences 2020-01-01
coleção:	Advanced Pharmaceutical Bulletin
Assuntos:	alpha7 nicotinic acetylcholine receptor small interfering rna nicotine hepg2 apoptosis
Acesso em linha:	https://apb.tbzmed.ac.ir/PDF/apb-27763
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