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Frequency and spectrum of MT-TT variants associated with Leber’s hereditary optic neuropathy in a Chinese cohort of subjects

Leber’s hereditary optic neuropathy (LHON) is a maternally inherited eye disease. In our previous investigations, we have reported the spectrum and frequency of mitochondrial MT-ND1, MT-ND4 and MT-ND6 gene in Chinese LHON population. This study aimed to assess the molecular epidemiology of MT-TT mut...

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Principais autores: Yuanyuan Lyu, Man Xu, Jie Chen, YanChun Ji, Min-Xin Guan, Juanjuan Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2019-07-01
Serier:Mitochondrial DNA. Part B. Resources
Fag:
leber’s hereditary optic neuropathy (lhon)
mt-tt gene
variant
spectrum
chinese
Online adgang:http://dx.doi.org/10.1080/23802359.2019.1627921
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