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NKG2D ligand tumor expression and association with clinical outcome in early breast cancer patients: an observational study

<p>Abstract</p> <p>Background</p> <p>Cell surface NKG2D ligands (NKG2DL) bind to the activating NKG2D receptor present on NK cells and subsets of T cells, thus playing a role in initiating an immune response. We examined tumor expression and prognostic effect of NKG2DL in breast cancer patients.</p>...

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Principais autores: de Kruijf Esther M, Sajet Anita, van Nes Johanna GH, Putter Hein, Smit Vincent THBM, Eagle Robert A, Jafferji Insiya, Trowsdale John, Liefers Gerrit, van de Velde Cornelis JH, Kuppen Peter JK
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2012-01-01
coleção:BMC Cancer
Assuntos:
ULBP
MIC
NKG2D ligand
breast cancer
immune evasion
Acesso em linha:http://www.biomedcentral.com/1471-2407/12/24
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