Epistatic relationships between sarA and agr in Staphylococcus aureus biofilm formation.

The accessory gene regulator (agr) and staphylococcal accessory regulator (sarA) play opposing roles in Staphylococcus aureus biofilm formation. There is mounting evidence to suggest that these opposing roles are therapeutically relevant in that mutation of agr results in increased biofilm formation...

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Principais autores:	Karen E Beenken, Lara N Mrak, Linda M Griffin, Agnieszka K Zielinska, Lindsey N Shaw, Kelly C Rice, Alexander R Horswill, Kenneth W Bayles, Mark S Smeltzer
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2010-05-01
Colecção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC2875390?pdf=render
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