Early pathogenesis profiles across SARS-CoV-2 variants in K18-hACE2 mice revealed differential triggers of lung damages

The on-going COVID-19 pandemic has given rise to SARS-CoV-2 clades and variants with differing levels of symptoms and severity. To this end, we aim to systematically elucidate the changes in the pathogenesis as SARS-CoV-2 evolved from ancestral to the recent Omicron VOC, on their mechanisms (e.g. cy...

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Bibliografische gegevens

Hoofdauteurs:	Zhen Qin Aw, Chee Keng Mok, Yi Hao Wong, Huixin Chen, Tze Minn Mak, Raymond T. P. Lin, David Chien Lye, Kai Sen Tan, Justin Jang Hann Chu
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Frontiers Media S.A. 2022-10-01
Reeks:	Frontiers in Immunology
Onderwerpen:	SARS-CoV-2 variants of concern immune response cytokine storm K18-hACE2 mice model
Online toegang:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.950666/full
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