The Role and Mechanism of Hyperoside against Depression-like Behavior in Mice via the NLRP1 Inflammasome

Background and Objectives: <i>Hypericum perforatum</i> (HP) is widely used for depressive therapy. Nevertheless, the antidepressant effect and potential mechanism of hyperoside (Hyp), the main active component of HP, have not been determined. Materials and Methods: We performed ultra-performance liq...

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Главные авторы:	Aoqi Song, Zhenghua Wu, Wenjuan Zhao, Wenqing Shi, Ru Cheng, Jingjing Jiang, Zhuojun Ni, Han Qu, Xijier Qiaolongbatu, Guorong Fan, Yuefen Lou
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2022-11-01
Серии:	Medicina
Предметы:	depression NLRP1 inflammasome <i>Hypericum perforatum</i> hyperoside CXCL1/CXCR2 BDNF
Online-ссылка:	https://www.mdpi.com/1648-9144/58/12/1749
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