Simultaneous Blockade of Histamine H₃ Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf/J Mouse Model of Autism

Autism spectrum disorder (ASD) is a heterogenous neurodevelopmental disorder defined by persistent deficits in social interaction and the presence of patterns of repetitive and restricted behaviors. The central neurotransmitters histamine (HA) and acetylcholine (ACh) play pleiotropic roles in physio...

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Hlavní autoři:	Nermin Eissa, Petrilla Jayaprakash, Holger Stark, Dorota Łażewska, Katarzyna Kieć-Kononowicz, Bassem Sadek
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2020-08-01
Edice:	Biomolecules
Témata:	autism spectrum disorder BTBR mice histamine histamine H<sub>3</sub> receptor antagonist acetylcholine acetylcholine esterase inhibitor
On-line přístup:	https://www.mdpi.com/2218-273X/10/9/1251
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