Tumor immunotherapies by immune checkpoint inhibitors (ICIs); the pros and cons

Abstract The main breakthrough in tumor immunotherapy was the discovery of immune checkpoint (IC) proteins, which act as a potent suppressor of the immune system by a myriad of mechanisms. After that, scientists focused on the immune checkpoint molecules mainly. Thereby, much effort was spent to pro...

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Библиографические подробности

Главные авторы:	Adel Naimi, Rebar N. Mohammed, Ahmed Raji, Supat Chupradit, Alexei Valerievich Yumashev, Wanich Suksatan, Mohammed Nader Shalaby, Lakshmi Thangavelu, Siavash Kamrava, Navid Shomali, Armin D. Sohrabi, Ali Adili, Ali Noroozi-Aghideh, Ehsan Razeghian
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2022-04-01
Серии:	Cell Communication and Signaling
Предметы:	Immune checkpoint inhibitors CTLA-4 PD-1/PD-L1 Cancer Immunotherapy
Online-ссылка:	https://doi.org/10.1186/s12964-022-00854-y
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